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Ed and Al return this lack of regard, though since they don't view the flashbacks they may never actually see it put in these terms. He seems to restrict those completely to his children he also doesn't address Hohenheim as his father.
Even when Ed and Al first meet Father, he fixes them up since they're his precious human sacrifices and is fascinated to discover that they're Van Hohenheim's sons and Hohenheim is still alive after all these years, but doesn't therefore think of them in even vaguely familial terms. But no one makes anything of this within the series. This relationship means that the homunculi are all technically Ed's nieces and nephews. Complicated by the fact that this 'son' was also kind of his mentor, giving him a name instead of a number and teaching him to read.
In Fullmetal Alchemist, it turns out that the Big Bad is kind of Ed and Al's elder brother, since he recognized their father as his father, back before he pulled From Nobody to Nightmare, and turned Hohenheim into a monster, too. Later on, it turns out Natsu is Zeref's younger brother, or rather his resurrected younger brother. During the Edolas Arc Happy unknowingly runs into his parents while escaping from the Exceed. His brother, however, is younger and much weaker, and apparently Vegeta knew of his existence already. More than a decade later, the new Dragon Ball Z special gives Vegeta a brother as well. Dragon Ball Z kicks off with the dual revelations that Goku A) is an alien and B) has a much stronger evil older brother. (2005), Jet Seigel's brother Zack carbon-copies Racer X perfectly - he fakes his own death, then returns under the guise of Phantom Knight, with only his driving skills clueing Jet (and the audience) in on who he is.
In Chance Pop Session, Akari, Yuki and Nozomi all meet at Kisaragi's music school, not only becoming friends, but harmonizing together well enough to become a successful pop trio, only to learn they are all long-lost sisters, and that the woman who trained them is their mother!.In Brave10, although it takes a lot to jog her memory given how greatly he's changed over the years, it turns out Seikai really is Isanami's adoptive elder brother.Ichigo is also eventually revealed to be related to Uryuu, as his mother was the cousin of Uryuu's father. Bleach: Ichigo is eventually revealed to be the cousin of Kaien, Kuukaku and Ganju through his father (their uncle), explaining why Ichigo and Kaien look so alike.Asta's mother Licita abandoned him due to her body stealing magic and life from living things near her, and adopted Liebe as her child. Black Clover: Liebe, the devil in Asta's grimoire, is actually this to Asta, being his adoptive brother.Kenny also eventually reveals that he was Levi's maternal uncle, and that was the reason for taking him in as a child.
Mikasa and Levi learn that they are distant relatives, both members of the near-extinct Ackerman Clan. It was almost a decade before she met her father for the first time. Krista Lenz/Historia Reiss and her father, Rod Reiss. After escaping execution, Grisha started over and never told Eren about his original family. A Justified case with Eren and Zeke Yeager, half-brothers that only learn about each other after crossing paths on opposing sides.